Accelerating botanical drug delivery, dietary supplements, and therapeutic formulations through validated laboratory methods and pharmaceutical-grade industrial production.
Closing the analytical divide between ancient Traditional Chinese Medicine (TCM) pharmacopeias and Western regulatory requirements (FDA 21 CFR Part 111/211, EMA, WHO).
Global herbal sourcing has suffered historically from batch variation, environmental soil differences, and pesticide drift. MedGence solves this with validated chromatographic fingerprinting (HPTLC, HPLC-MS, GC-MS), establishing uniform analytical criteria across 100% of finished lots.
Many botanical compounds present low gastrointestinal solubility. Our proprietary solid dispersion, liposomal encapsulation, and micro-emulsification technologies elevate active molecule absorption (e.g., ginsenosides, curcuminoids, berberine) without chemical alterations.
Every commercial delivery includes rigorous documentation: heavy metal spectroscopy (ICP-MS), pesticide residue panels covering over 400 compounds via USP <561>, microbial screening, and stability protocols complying with ICH Q1A guidelines.
Leading the technological transition from traditional solvent decoction to intelligent molecular engineering and supercritical extraction architectures.
AI-assisted high-content phenotypic screening matching complex botanical phytocomplexes against cellular receptor targets, drastically cutting assay timeframes.
Supercritical CO2 and dual-frequency countercurrent ultrasonic continuous extraction preserving thermolabile terpenes and bioflavonoids cleanly without hazardous residue.
Process Analytical Technology (PAT) incorporating real-time In-line Near-Infrared (NIR) spectroscopic monitoring to control active concentration through every column.
Hybrid pipeline bridging wild-harvest cultivation with enzymatic biocatalysis to scale rare secondary metabolites that cannot be harvested sustainably from raw nature.
Strategic formulation design tailored precisely to the compliance and market landscape of tier-1 global brands.
Full-package solutions for functional blends, nootropic stacks, immune complexes, and metabolic wellness formulas. Finished formats: vegetarian capsules, softgels, micro-tablets, functional effervescents, and instant botanical dry granules.
Extensive support for botanical IND/NDA submissions under US FDA Botanical Drug Guidance. We handle CMC documentation, GLP safety toxicology assessments, pharmacokinetic characterization, and Phase I–IV clinical study designs.
High-purity botanical actives optimized for cellular barrier repair, melanogenesis inhibition, and photo-aging prevention. Every raw compound is backed by in vitro human dermal cell assays and non-animal irritation safety verification.
| Target Dosage Form | Technical Challenges Solved | Analytical Delivery Protocol | Commercial Capacity |
|---|---|---|---|
| Dry Extract Powders | Hygroscopicity reduction, uniform bulk density, instant cold-water solubility | HPLC potency assay, USP <561> pesticide screen | 1,200 MT / year |
| Encapsulated Softgels | Hydrophobic compound suspension, cross-linking stability in gelatin/tapioca | Rupture testing, total degradation profiling | 450 Million units / year |
| Concentrated Oral Liquids | Polyphenol precipitation, thermal degradation, harsh organoleptic masking | Accelerated shelf-life stability (ICH), HPTLC fingerprint | 80 Million bottles / year |
| Micro-Pellets / Granules | Controlled dissolution kinetics, moisture barriers, enteric protection | Dissolution apparatus test (USP 711), particle size mesh laser scan | 800 MT / year |
By consolidating scientific crop harvesting, pilot development, and massive manufacturing, we insulate your supply chain from price volatility and quality disruptions.
Over 12,000 hectares of partnered Good Agricultural Practice (GAP) cultivation bases situated throughout primary production belts in Hunan, Sichuan, Yunnan, and Guizhou ensure pure cultivar identity, seed provenance, and early harvest optimization.
Avoid scaling failures. Our proprietary pilot plant uses dynamically matched geometry between 50L experimental reactors and 10,000L commercial extraction vessels, ensuring yield models, thermodynamics, and recovery rates convert seamlessly without batch loss.
We work as an entrusted, non-competing CDMO partner. Formula parameters, compound blending sequences, analytical profiles, and customer process IP are protected under strict NDA legal agreements, air-gapped laboratory databases, and dedicated clean-room suites.
Trusted by tier-one pharmaceutical groups, university teaching hospitals, and international supplement innovators across 30+ countries.
Comprehensive New Dietary Ingredient (NDI) filings and Generally Recognized as Safe (GRAS) toxicological dossiers, backed by GLP-certified 90-day subchronic and mutagenicity studies.
Scientific demonstration of history of safe consumption, chromatographic equivalency to European Pharmacopoeia monographs, and full polycyclic aromatic hydrocarbon (PAH) residual validation.
100% plant-based excipient options: replacing synthetic flow agents (silicon dioxide, magnesium stearate) with native organic rice husks, pullulan, and clean acacia fibers.
Tongrentang Group
China Resources Sanjiu
Sunflower Pharma
Livzon Pharma
Dihon Pharmaceutical
Golden Throat Group
Yangtzi River Pharma
Humanwell Healthcare
Detailed technical answers for procurement directors, product developers, and regulatory compliance teams.
Explore our complete range of plant screening, clinical assessment, and custom formulation services.
